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ccdc80 polyclonal antibody  (Biorbyt)


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    Biorbyt ccdc80 polyclonal antibody
    The expression of <t>CCDC80</t> protein in normal ovary (a) and (b) and ovarian carcinoma (c) and (d) tissues through immunohistochemical (IHC) staining.
    Ccdc80 Polyclonal Antibody, supplied by Biorbyt, used in various techniques. Bioz Stars score: 93/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ccdc80 polyclonal antibody/product/Biorbyt
    Average 93 stars, based on 3 article reviews
    ccdc80 polyclonal antibody - by Bioz Stars, 2026-02
    93/100 stars

    Images

    1) Product Images from "Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study"

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    Journal: International Journal of Genomics

    doi: 10.1155/2021/3752871

    The expression of CCDC80 protein in normal ovary (a) and (b) and ovarian carcinoma (c) and (d) tissues through immunohistochemical (IHC) staining.
    Figure Legend Snippet: The expression of CCDC80 protein in normal ovary (a) and (b) and ovarian carcinoma (c) and (d) tissues through immunohistochemical (IHC) staining.

    Techniques Used: Expressing, Immunohistochemical staining, Immunohistochemistry

    Scatter plots of CCDC80 protein (a) and mRNA (b)–(i) expression of OVCA and the corresponding normal controls.
    Figure Legend Snippet: Scatter plots of CCDC80 protein (a) and mRNA (b)–(i) expression of OVCA and the corresponding normal controls.

    Techniques Used: Expressing

    The receiver operating characteristic (ROC, (a)–(i)) and sROC (j) curves of CCDC80 in OVCA and Deek's test for publication bias test (k).
    Figure Legend Snippet: The receiver operating characteristic (ROC, (a)–(i)) and sROC (j) curves of CCDC80 in OVCA and Deek's test for publication bias test (k).

    Techniques Used:

    Combined standard mean difference (SMD, (a)) of CCDC80 expression between OVCA and non-OVCA group and Egger's test (b) for publication bias test (in mRNA group, TCGA_GTEx_ovary was a cohort of RNA-seq, and other cohorts began with “GSE” were gene chip cohorts).
    Figure Legend Snippet: Combined standard mean difference (SMD, (a)) of CCDC80 expression between OVCA and non-OVCA group and Egger's test (b) for publication bias test (in mRNA group, TCGA_GTEx_ovary was a cohort of RNA-seq, and other cohorts began with “GSE” were gene chip cohorts).

    Techniques Used: Expressing, RNA Sequencing

    The relationship between CCDC80 expression and the fraction of immune cell infiltration in OVCA based on CIBERSORT algorithms.
    Figure Legend Snippet: The relationship between CCDC80 expression and the fraction of immune cell infiltration in OVCA based on CIBERSORT algorithms.

    Techniques Used: Expressing

    The boxplots visualizing the single-sample gene set enrichment analysis (ssGSEA) in high- and low- CCDC80 expression group in OVCA based on immunocyte-related gene sets (a) and immune function-related gene sets (b) ( ∗∗∗ , P < 0.0001; ∗∗ , P < 0.001; ∗ , P < 0.05; ns, P ≥ 0.05).
    Figure Legend Snippet: The boxplots visualizing the single-sample gene set enrichment analysis (ssGSEA) in high- and low- CCDC80 expression group in OVCA based on immunocyte-related gene sets (a) and immune function-related gene sets (b) ( ∗∗∗ , P < 0.0001; ∗∗ , P < 0.001; ∗ , P < 0.05; ns, P ≥ 0.05).

    Techniques Used: Expressing

    KEGG enrichment plots of the intersection genes from CCDC80 positively related coexpressed genes (CEGs) and downregulated differentially expressed genes (DEGs) (a), and CCDC80 negatively related CEGs and upregulated DEGs (b).
    Figure Legend Snippet: KEGG enrichment plots of the intersection genes from CCDC80 positively related coexpressed genes (CEGs) and downregulated differentially expressed genes (DEGs) (a), and CCDC80 negatively related CEGs and upregulated DEGs (b).

    Techniques Used:

    A volcano plot shows the results of GSEA based on the OVCA cell lines and enrichment plots of immune-related gene sets in low- CCDC80 group (b) and (c) and high- CCDC80 group (d) and (e).
    Figure Legend Snippet: A volcano plot shows the results of GSEA based on the OVCA cell lines and enrichment plots of immune-related gene sets in low- CCDC80 group (b) and (c) and high- CCDC80 group (d) and (e).

    Techniques Used:

    Seqlogos of the motifs of transcription factor NR3C1 (a) and PBX3 (b); ChIP-seq peak (see red arrow) of NR3C1 in the upstream of the transcription start site of CCDC80 (c); and the yellow arrow indicates the transcription direction of CCDC80 ; no ChIP-seq peak of PBX3 in the upstream of the transcription start site of CCDC80 (d).
    Figure Legend Snippet: Seqlogos of the motifs of transcription factor NR3C1 (a) and PBX3 (b); ChIP-seq peak (see red arrow) of NR3C1 in the upstream of the transcription start site of CCDC80 (c); and the yellow arrow indicates the transcription direction of CCDC80 ; no ChIP-seq peak of PBX3 in the upstream of the transcription start site of CCDC80 (d).

    Techniques Used: ChIP-sequencing

    Violin plots visualizing the differences of estimated half maximal inhibitory concentration (IC50) of compounds between high- and low- CCDC80 expression group.
    Figure Legend Snippet: Violin plots visualizing the differences of estimated half maximal inhibitory concentration (IC50) of compounds between high- and low- CCDC80 expression group.

    Techniques Used: Concentration Assay, Expressing



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    ccdc80 polyclonal antibody  (Biorbyt)
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    The expression of <t>CCDC80</t> protein in normal ovary (a) and (b) and ovarian carcinoma (c) and (d) tissues through immunohistochemical (IHC) staining.
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    Image Search Results


    ( A ) Representative IHC images of COl2, MMP13, and CCDC80 staining in meniscus lesions of the knee joint. ( B ) Quantification of IHC staining intensity for COl2, MMP13, and CCDC80. ( C ) Multivariate analyses of COl2, MMP13 and CCDC80 using GEE to understand the independent therapeutic effect of IOP and hydrogel in the meniscus lesions. All data are shown as means ± standard deviations (n= 6). * P ≤0.05, **** P ≤0.0001. GEE: Generalized Estimating Equation.

    Journal: bioRxiv

    Article Title: Evaluating the Therapeutic Efficacy of Iopanoic Acid in a DMM-Induced Osteoarthritis Mouse Model and Osteochondral Lesioned Human Explants

    doi: 10.1101/2025.07.15.663868

    Figure Lengend Snippet: ( A ) Representative IHC images of COl2, MMP13, and CCDC80 staining in meniscus lesions of the knee joint. ( B ) Quantification of IHC staining intensity for COl2, MMP13, and CCDC80. ( C ) Multivariate analyses of COl2, MMP13 and CCDC80 using GEE to understand the independent therapeutic effect of IOP and hydrogel in the meniscus lesions. All data are shown as means ± standard deviations (n= 6). * P ≤0.05, **** P ≤0.0001. GEE: Generalized Estimating Equation.

    Article Snippet: Primary CCDC80 antibody incubation was done overnight at 4 C with 2μg/mL CCDC80 polyclonal antibody (A65521, Thermo Fisher Scientific, Waltham, MA, USA) or with 2 μg/mL normal mouse IgG1 as isotype control (sc3877, Santa Cruz, Dallas, TX, USA).

    Techniques: Staining, Immunohistochemistry

    The expression of CCDC80 protein in normal ovary (a) and (b) and ovarian carcinoma (c) and (d) tissues through immunohistochemical (IHC) staining.

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: The expression of CCDC80 protein in normal ovary (a) and (b) and ovarian carcinoma (c) and (d) tissues through immunohistochemical (IHC) staining.

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques: Expressing, Immunohistochemical staining, Immunohistochemistry

    Scatter plots of CCDC80 protein (a) and mRNA (b)–(i) expression of OVCA and the corresponding normal controls.

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: Scatter plots of CCDC80 protein (a) and mRNA (b)–(i) expression of OVCA and the corresponding normal controls.

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques: Expressing

    The receiver operating characteristic (ROC, (a)–(i)) and sROC (j) curves of CCDC80 in OVCA and Deek's test for publication bias test (k).

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: The receiver operating characteristic (ROC, (a)–(i)) and sROC (j) curves of CCDC80 in OVCA and Deek's test for publication bias test (k).

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques:

    Combined standard mean difference (SMD, (a)) of CCDC80 expression between OVCA and non-OVCA group and Egger's test (b) for publication bias test (in mRNA group, TCGA_GTEx_ovary was a cohort of RNA-seq, and other cohorts began with “GSE” were gene chip cohorts).

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: Combined standard mean difference (SMD, (a)) of CCDC80 expression between OVCA and non-OVCA group and Egger's test (b) for publication bias test (in mRNA group, TCGA_GTEx_ovary was a cohort of RNA-seq, and other cohorts began with “GSE” were gene chip cohorts).

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques: Expressing, RNA Sequencing

    The relationship between CCDC80 expression and the fraction of immune cell infiltration in OVCA based on CIBERSORT algorithms.

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: The relationship between CCDC80 expression and the fraction of immune cell infiltration in OVCA based on CIBERSORT algorithms.

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques: Expressing

    The boxplots visualizing the single-sample gene set enrichment analysis (ssGSEA) in high- and low- CCDC80 expression group in OVCA based on immunocyte-related gene sets (a) and immune function-related gene sets (b) ( ∗∗∗ , P < 0.0001; ∗∗ , P < 0.001; ∗ , P < 0.05; ns, P ≥ 0.05).

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: The boxplots visualizing the single-sample gene set enrichment analysis (ssGSEA) in high- and low- CCDC80 expression group in OVCA based on immunocyte-related gene sets (a) and immune function-related gene sets (b) ( ∗∗∗ , P < 0.0001; ∗∗ , P < 0.001; ∗ , P < 0.05; ns, P ≥ 0.05).

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques: Expressing

    KEGG enrichment plots of the intersection genes from CCDC80 positively related coexpressed genes (CEGs) and downregulated differentially expressed genes (DEGs) (a), and CCDC80 negatively related CEGs and upregulated DEGs (b).

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: KEGG enrichment plots of the intersection genes from CCDC80 positively related coexpressed genes (CEGs) and downregulated differentially expressed genes (DEGs) (a), and CCDC80 negatively related CEGs and upregulated DEGs (b).

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques:

    A volcano plot shows the results of GSEA based on the OVCA cell lines and enrichment plots of immune-related gene sets in low- CCDC80 group (b) and (c) and high- CCDC80 group (d) and (e).

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: A volcano plot shows the results of GSEA based on the OVCA cell lines and enrichment plots of immune-related gene sets in low- CCDC80 group (b) and (c) and high- CCDC80 group (d) and (e).

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques:

    Seqlogos of the motifs of transcription factor NR3C1 (a) and PBX3 (b); ChIP-seq peak (see red arrow) of NR3C1 in the upstream of the transcription start site of CCDC80 (c); and the yellow arrow indicates the transcription direction of CCDC80 ; no ChIP-seq peak of PBX3 in the upstream of the transcription start site of CCDC80 (d).

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: Seqlogos of the motifs of transcription factor NR3C1 (a) and PBX3 (b); ChIP-seq peak (see red arrow) of NR3C1 in the upstream of the transcription start site of CCDC80 (c); and the yellow arrow indicates the transcription direction of CCDC80 ; no ChIP-seq peak of PBX3 in the upstream of the transcription start site of CCDC80 (d).

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques: ChIP-sequencing

    Violin plots visualizing the differences of estimated half maximal inhibitory concentration (IC50) of compounds between high- and low- CCDC80 expression group.

    Journal: International Journal of Genomics

    Article Title: Downregulation of the Coiled-Coil Domain Containing 80 and Its Perspective Mechanisms in Ovarian Carcinoma: A Comprehensive Study

    doi: 10.1155/2021/3752871

    Figure Lengend Snippet: Violin plots visualizing the differences of estimated half maximal inhibitory concentration (IC50) of compounds between high- and low- CCDC80 expression group.

    Article Snippet: Afterward, immunohistochemical (IHC) staining conducted using CCDC80 polyclonal antibody (biorbyt, orb216089, rabbit-anti-human) with 150 OVCA tissues and 46 non-OVCA tissues from clinical samples and tissue microarrays.

    Techniques: Concentration Assay, Expressing